Metformin for Weight Loss
For Weight Loss is a medicine that comes in the form of different shaped
tablets, all of which have to be taken orally. It is a drug most doctors will
prescribe first in patients with type 2 diabetes, especially if they are
overweight or even obese. When used properly, Metformin weight loss
causes almost no negative side effects apart from maybe upset your stomach
and/or bowls (causing diarrhea, cramps, nausea, vomiting and increased
windiness). Be sure not to take an overdose, as this may cause Lactic Acidosis.
Be sure to talk to your doctor before using Metformin weight loss! Metformin
probably is the most used anti-diabetes medicine world-wide, with over 40
million prescriptions just in the US in 2008. Metformin is the generic name,
brand names includes Glucophage XR, Riomet, Fortamet, Glumetza, Obimet,
Dianben, Diabex, and Diaformin.
Metformin for Weight Loss-
How can Metformin HCl help you to
slim down? Well, in short, it will reduce your feeling of being hungry. If your
most important overweight problem area is your belly, then there is a good
chance you are overweight on the account of too much insulin production. Eating
makes your blood sugar level rise and the higher it goes, the more insulin your
Pancreas produces. This insulin tells your brain to feel hungry, your liver to
manufacture fat, and the fat cells in your waist area to suck up this fat. To
fight this kind of obesity and lose weight, you need to stay away from food
that makes your blood sugar rise excessively and to take Metformin which
prevents your blood sugar level to rise too much. Stay away from flour made
foods like bread, pastry and pasta, fruit juices and basically anything that
has sugar added to it. Consume fruit and potatoes only with meals. The weight
loss effects of Metformin are reduced by excess lactic acids in your blood, but
working out does not make those acid levels rise enough to counteract the weight
loss benefits. So no, taking Metformin is no excuse to stop exercising. Daily
exercising will always stay number 1 when it comes to losing weight. Metformin
is safe and effective as weight loss alternative, but you will not see any
benefits if you keep eating food that increases your blood sugar quickly. It
does not help you lose weight taking Metformin after indulging in 2 slices of
Cherry Pie. Common prescription of Metformin dosage for weight loss: 500mg a
few minutes before meals, 3 times a day.
Should Not Take Metformin Weight Loss-
should NOT take Metformin Weight Loss if you suffer from a kidney disorder, if
you have a lung or liver disease, any case of heart failure, or in general any
condition that would heighten the chances of Lactic Acidosis or make your blood
acidic. Neither should you take Metformin Weight Loss when you are
breast-feeding. There are scores of other medicines you should not be taking
Metformin in combination with, so definitely consult your doctor if you are
taking other prescription drugs. Stop taking Metformin temporarily before
undergoing any procedure that involves iodinated contrast as this liquid may temporarily
hinder the correct working of the kidney. You should be ok to continue after 2
days. If you’re serious about losing weight, you might want to check out the
Top Non-Travel Weight-Loss Boot camp available.
Metformin and Polycystic
Ovary Syndrome (PCOS) - Metformin Is The Top Drug For PCOS
- Metformin and PCOS
named together as Metformin is very effective and powerful in treatment of
PCOS. Polycystic Ovary Syndrome (PCOS) will reveal itself with symptoms
associated with dysfunction of ovulation, hyperandrogenism, resistance to
insulin and hyperinsulinemia. PCOS affects 7 to 9% of women of reproductive
age. Research says that PCOS may have a genetic link. A germ line mutation of
the insulin receptor gene may cause insulin resistance. Insulin resistance can
be defined as decreased response of glucose to an amount of insulin given. Not
all insulin resistant women are hyperandrogenic; there are some more mechanisms
that explain impaired glucose tolerance. These can be decrease hepatic
clearance or improper pancreatic function. Hyperinsulinemia may cause hypertension
which on it turn may result in cardiovascular disease. People who are having
body mass index 25 to 30 kg/M2 can be categorized as overweight and those who
are having body mass index more than 30 kg/M2 are obese. Women having body mass
index more 25 kg/M2 are more prone to ovulation dysfunction. Almost all obese
and overweight women are insulin resistant. They will have a typical body fat
distribution, which is called an android obesity causing reduced level of Sex
Hormone Binding Globulin, which in turn, results in increased risk of
cardiovascular diseases. Other symptoms of PCOS are acne, hair loss and
hisutism (hyperandrogenism), reproductive diseases (irregular menses, impaired
ovulation, polycystic ovaries etc.), weight gain may be associated with hyperinsulinemia
and insulin resistance. By the age 40 to 45 years, in 30 to 40% of Polycystic
Ovary Syndrome (PCOS) patients, insulin resistance or clinical diabetes will
occur. They may experience sudden abortions. Hyperinsulinemia caused by insulin
resistance may result in short and long term clinical manifestation of PCOS.
The title “Metformin and PCOS
refers to the fact that Metformin is the number one drug prescribed in the
treatment of PCOS. Metformin is a generic name for the brand of
Glucophage or Glucophage XR. Being an insulin sensitizing Biguanide it
increases the blood glucose level in Type 2 Diabetics. Metformin increases the
cell’s response towards insulin and helps glucose to move into your cell
causing the body not to make much insulin.
Studies show that Metformin improves
ovulation, irregular menses, hirsutism, delay the onset of diabetes, decreases
the levels of testosterone, insulin and glucose, improves chances of pregnancy,
decreases risk of miscarriage, Metformin weight loss etc. However it is always
certain that weight loss by doing routine exercise, healthy diet and clean life
style also improves menstrual cycles and hyperandrogenism. Metformin can be
found in three different forms:
The generic Metformin HCL ,
(brand name) , Glucophrage XR (brand name)
Metformin has very minimal Metformin
side effects in gastrointestinal system. Using Metformin may cause more fat
deposition in blood, pregnancy complication, anemia etc.
Metformin is contraindicated in case
of liver failure, improper renal function, alcoholism, hypoxia and infections. During
the intake of Metformin, improve your food habit, do routine exercise, add
extra nutrition to your diet (fish oil, biotin, vitamin E etc.) and take good
quality vitamin and mineral supplement.
and Alcohol Consumption – Risks :
When taking Metformin to control type 2 diabetes it is not
recommended to consume large amounts of alcohol. Drinking alcohol can increase
the risk of a potentially life threatening condition called lactic acidosis.
This is where the body produces a buildup of lactic acid that cannot be
neutralized quickly enough. When this happens the patient will feel nauseous
and may have vomiting, a low blood pressure and a rapid pulse. If lactic
acidosis is suspected then medical advice should be sought immediately.
And Alcohol Interaction-
are first prescribed Metformin by your health practitioner, you should, if in
doubt, ask whether it is safe to drink alcohol while taking the medication. Ask
him if it is safe to mix Metformin and alcohol. It is generally thought that
small quantities of alcohol do not harm the treatment. The occasional glass of
red wine is supposed to be beneficial to health. It must be remembered though
that the aim of taking Metformin as a diabetes treatment is to lower the blood
sugar levels. If a lot of alcohol is used in cooking, the sugars from the
alcohol remain after the spirit has been burnt off, and should be taken into
consideration if you have been placed on a calorie controlled diet by your
And Alcohol Side Effects-
One of the
long term effects of excessive alcohol consumption is liver damage; this can
manifest itself as cirrhosis. This affects the livers ability to process the
sugars in your system, and if Metformin is taken, the chances of lactic
acidosis will greatly increase. It must be stated though that Metformin will
not actually induce lactic acidosis but if there are other health related
issues, then being prescribed the tablets and not informing your health
practitioner will only compound the problem. On being prescribed Metformin,
patients should not feel any adverse effects if they drink moderately. There
are those that will tell you that alcohol lowers the blood sugar levels and
whilst this may be true, lower levels can result in hypoglycemia. If this is
suspected, hospital treatment should be sought immediately.
Whilst it may be felt that Metformin
could seriously inhibit your social life, this need not be necessarily
so. Any patient who is using the tablets can take one of two courses of
action with regard to alcohol consumption when in a social environment. One is
to abstain completely, maybe nominating themselves as the designated driver or
telling their companions the reason for their abstinence; or they can have one
or two drinks and then change to a non alcoholic drink.
Consumption of alcohol is also
associated with weight gain and if you are using Metformin as a dietary measure
to lose weight there will be a negative effect if alcohol is drunk too often.
So the overall thoughts of combining
Metformin and alcohol
is that provided moderation is practiced, then the
occasional alcoholic drink will not be harmful, but excessive alcohol
intake must be avoided when on the treatment. Practicing restraint will ensure
your health will remain good and the treatment will work as it is supposed to.
Most Commonly Experienced Metformin Side Effects -
When you take Metformin as directed by your doctor, there
should be almost no negative side effects.
What Are The Side Effects of Metformin?
Most common experienced Metformin side effects
include an upset stomach and/or bowls and as a result, you could suffer from
diarrhea, cramps and experience increased flatulence. You could feel nauseous
and may have to vomit.
to Avoid the Negative Metformin Side Effects?
To avoid these negative side effects, start of with a
smaller Metformin Dosage (750 mg per day, half a 500mg pill per meal) and work
up from there. Or use Metformin SR (slow release) or XR (extended release),
which are specially designed to lessen the side effects of Metformin.
Are the Side Effects of Metformin to Report Immediately-
Immediately report any sign of lactic acidosis to your
Lactic acidosis is when lactic acid
builds up in the bloodstream faster than it can be removed. Lactic acid is
produced when oxygen levels in the body drop. The most common cause of lactic
acidosis is intense exercise. However, it can also be caused by certain
diseases, such as: AIDS, Cancer, Kidney failure, Respiratory failure, Sepsis.
Signs of lactic acidosis include
feeling tired or weak, nausea, experience muscle pain, having trouble
breathing, persistent stomach pain, feeling cold, experiencing dizziness or
feeling lightheaded, and a slow or irregular heartbeat. People taking Metformin
Weight Loss should have their electrolyte levels checked 1 – 2 weeks after
starting taking it,
What are the side effects of
Metformin you should also report to your doctor?
Other Metformin side effects
to report are
indications of high levels of blood sugar (like increased hunger, thirst or
urination; blurred vision; fatigue; shortness of breath) or, to the contrary,
symptoms of low blood sugar (like sweating, cold sweats, shakiness, extreme
hunger, dizziness, blurry vision, behavior changes , such as becoming
over-irritability, loss of coordination, difficulty speaking, confusion,
As with all drugs you take for the
first time, also report any unexplainable chest pains or signs of allergic
reaction, as they might indicate an unwanted and maybe dangerous side effect.
In clinical studies, a low
percentage of people experienced the following side effects: taste changes,
abnormal stools, nail problems, flu-like symptoms, such as fever, muscle pain,
chills, and weakness). However, the percentages were so low if is impossible to
deduct that these are Metformin side effects
or the result of something
It is important that you seek
medical attention immediately if you believe that you may have overdosed on
To The Physician’s Desk Reference-T
starting dose should be 500 mg of Metformin twice a day or alternatively 850 mg
once a day.
After one week, this dosage can be
increased to 1000 mg as the first dose of the day and 500 mg as the second
dose. In week 3, you can increase to 1000 mg of Metformin two times a day. The
maximum safe Metformin dosage described in the Physician’s Desk Reference is
2550 mg a day (which should be taken as 850 mg three times a day).
Two Types Metformin
It’s kind of hard to answer the
question if there are two different types of Metformin: it all depends on how
you look at “Two Types Metformin
“… You could differentiate between
Metformin and Glucophage. There’s the standard type of Metformin and the
“different” ER/XR version. And then there are the really different combinations
of Metformin with another drug.
Metformin is the generic name for
brand name Glucophage “Glucose Eater”.
vs Metformin ER/XR
Metformin ER/XR are the so called
extended or time release versions of standard Metformin. They were introduced
in 2004 to lower the risk on the negative Metformin side effects. Basically
they dissolve slower or “release” the active ingredient over a longer period of
time than standard Metformin.