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Phentermine for weight Loss

Phentermine , a contraction of " phenyl-tertiary-butylamine ", is a psychostimulant drug
of thephenethylamine class, with pharmacology similar to amphetamine.

Phentermine is used medically as an appetite suppressant to patients who are unable to curb their appetite them self.

Phentermine is approved by FDA as an appetite suppressant to help reduce weight in obese patients when used short-term and combined with exercise, diet, and behavioral modification. It is typically prescribed for individuals who are at increased medical risk because of their weight and works by helping to release certain chemicals in the brain that control appetite.

Strengths: 15mg 18.5 mg 30 mg 37.5 mg

What types of Phentermine are there?
Here are some of the Phentermine available;
Imprint 640  Phentermine Hydrochloride Strength 30mg
Imprint 647 Phentermine Hydrochloride  Strength 30mg capsules
Imprint 889 Phentermine HCL Strength 30mg  Capsule Red/Yellow
Imprint 3100 Phentermine HCL Strength 30mg Capsules Yellow
Imprint 1315 Phentermine Hydrochloride Strength 30mg Black
Imprint3925 Phentermine Hydrochloride Strength 30mg Blue and clear
Imprint Phentermine Hydrochloride Strength 30mg Blue and white
Imprint 25Phentermine Hydrochloride Strength 30mg

Medical uses

Phentermine is used for the short-term treatment of obesity.
Adverse effects
Generally, Phentermine appears to be relatively well tolerated. It can produce side effects consistent with its catecholamine-releasing properties, e.g., tachycardia (increased heart rate) and elevated blood pressure, but the incidence and magnitude of these appear to be less than with the amphetamines. Because Phentermine acts through sympathomimetic pathways, the drug may increase blood pressure and heart rate. It may also cause palpitations, restlessness, and insomnia. Additionally, Phentermine has the potential to cause psychological dependence. After short-term use, tolerance begins and can be followed by rebound weight gain.
Cardiovascular side effects include palpitations, tachycardia, and elevation of blood pressure. In the central nervous system, it can cause overstimulation, restlessness, dizziness, insomnia, euphoria, dysphoria, tremor, and headache. Its gastrointestinal effects include dryness of the mouth, unpleasant taste, diarrhea, constipation, and other gastrointestinal disturbances. It may also cause allergic effects - urticaria and changes in libido.
Its less common, but more severe, side effects include:

  • Convulsions (seizures)
  • Fever
  • Hallucinations
  • Hostility with urge to attack
  • Bizarre behavior
  • Mental or mood changes
  • Exaggerated sense of well-being
  • Irregular blood pressure
  • Severe or persistent light-headedness, fainting or headache
  • Periods of mania followed by period of depression
  • Fast or irregular heartbeat
  • Overactive reflexes
  • Tremors, trembling or shaking
  • Panic
  • Restlessness
  • Severe nausea, vomiting or diarrhea
  • Stomach cramps
  • Weakness
  • Constipation
  • Primary pulmonary hypertension
  • Regurgitant cardiac valvular disease
  • Pounding in the chest or shortness of breath

Cautions
Phentermine use is contraindicated in those who are:

  • Allergic to Phentermine, any of its metabolites or other sympathomimetic (e.g., pseudoephedrine)
  • Taking amphetamine (i.e., Adderall, Dexedrine, Vyvanse), bupropion (WellButrin), dexfenfluramine, fenfluramine, furazolidone, guanadrel, guanethidine, or have taken a monoamine oxidase inhibitor (MAOI) (e.g., phenelzine) in the last 14 days
  • Subject to severe high blood pressure, an overactive thyroid, glaucoma, heart or blood vessel disease, severe narrowing of the blood vessels, diabetes, a brain or spinal cord disorder, hardening of the arteries, or high cholesterol or lipid levels
  • In an agitated state, or have a history of substance abuse
  • Pregnant, planning to become pregnant, or are breast-feeding
  • Taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement

Medicines which may interact with Phentermine, such as dexfenfluramine, fenfluramine, furazolidone, or MAOIs (e.g., phenelzine) are contraindicated because of the risk of serious side effects, such as increasing headache, high blood pressure, slow heart rate, elevated temperature, or possibly fatal lung problems, may be increased. Guanadrel (Hylorel) or guanethidine (Ismelin) effectiveness may be decreased by Phentermine. Antacids may decrease the excretion of Phentermine. Carbonic anhydrase inhibitors (acetazolamide, dichlorphenamide, methazolamide) may decrease the excretion of Phentermine.
Mechanism of action
Phentermine works on the hypothalamus portion of the brain to stimulate the adrenal glands to release norepinephrine, a neurotransmitter or chemical messenger that signals a fight-or-flight response, reducing hunger. Phentermine works outside the brain, as well, to release epinephrine or adrenaline, causing fat cells to break down stored fat, but the principal basis of efficacy is hunger-reduction. At clinically relevant doses, Phentermine also releases serotonin and dopamine, but to a much lesser extent than that of norepinephrine.
Dosing and administration
Generally, it is recommended by the U.S. Food and Drug Administration (FDA) that Phentermine should be used short-term (usually interpreted as 'up to 12 weeks'), while following nonpharmacological approaches to weight loss such as healthy dieting and exercise.
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What is the standard Phentermine dosage?
Phentermine is available in the following doses; 15 mg, 18.5 mg, 30 mg and 37.5 mg.
People react differently to different doses of Phentermine. Your doctor should start you by prescribing the least amount needed to produce the desired effect of appetite suppression.
Doctors normally start their patients either on Phentermine 18.5 mg or half a pill of Phentermine 37.5 mg for economic reasons. Some Doctors prefer to prescribe Phentermine 15 mg initially and increase the dose if necessary. Each patient's reaction should be monitored and changes in dosage made according.
Phentermine is available in tablets or capsule form. The tablets can be spilt to halve the dosage but the capsules cannot be broken.
Popular daily doses of Phentermine are listed below. Most commonly one Phentermine diet pill is taken two hours after the breakfast, as breakfast is the most important meal of the day and calories consumes in morning gets used during the activities of the day. Phentermine is known to cause insomnia if taken too late in the day, this is another reason why it is taken midmorning.
Daily doses of Phentermine

  • 1 x 15 mg Phentermine two hours after breakfast
  • 1x18.5 mg Phentermine two hours after breakfast
  • 2 x 15 mg Phentermine (one two hours after breakfast and one between 5&6PM)
  • 2 x 18.75 mg Phentermine (one two hours after breakfast and one between 5&6PM)
  • 1 x 30 mg (extended release capsule) Phentermine two hours after breakfast
  • 1 x 30 mg (Capsule) Phentermine two hours after breakfast
  • 2x 30 mg Phentermine (one two hours after breakfast and one between 5&6PM)
  • 3x 30 mg Phentermine (one hours before each meal (last before 6PM)
  • 1 x 37.5 mg Phentermine two hours after breakfast
  • 1 ½ x 37.mg Phentermine (1 x 37.5 mg in the morning and half a tablet in the afternoon)
  • 2x 37.5 mg Phentermine (one two hours after breakfast and one between 5&6PM)

Over time your body may become used to the effects of Phentermine and your doctor may decide to increase your dosage to prolong the suppression of hunger throughout the day.


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